Analyze


1.   Platforms, prices, and company

o       Windows 95/98/NT/2000/ME, UNIX (Sun, SGI, HP, IBM, DEC Alpha) or Intel-based Linux

o       Mayo Foundation http://www.mayo.edu/bir/;   Analyze Direct: http://www.analyzedirect.com

2.   Applications

o       Analyze is an integrated, comprehensive software system developed by the Biomedical Imaging Resource, useful in a variety of multimodality, multidimensional biomedical imaging and scientific visualization applications. These integrated suites of complementary tools for fully interactive display, manipulation, and measurement of multidimensional biomedical images have been used in applications involving many different imaging modalities, including CT, MRI, SPECT, PET, ultrasound and digital microscopy.

3.   Examples/Samples

o       The Biomedical Imaging Resource at the Mayo Clinic: http://www.mayo.edu/bir/

o       Segmentation: http://www.analyzedirect.com/products/tour/images/screenshots/Segmented Objects.jpg

o       Image Fusion: http://www.analyzedirect.com/products/tour/images/screenshots/Fusion.jpg

o       Volume Render: http://www.analyzedirect.com/products/tour/images/screenshots/Volume Render.JPG
 
 

4.   Functions

o       The following summarizes the advanced algorithms and major features of the Analyze software system

o       Analyze Main Control Panel

§        Launching pad for all Analyze programs, either from menus or power bar icons.

§        Configurable, multiple power bar(s) for iconic representations of programs.

§        Control canvas for loaded volume images with iconic representation of images.

§        Configurable loaded volume location for multiple, independent sessions.

§        System resource monitor (disk, memory, time, etc.)

§        Powerbar editor and icon layout facility

§        Support for multiple user preferences (interface options, etc.)

o       Image Data Retrieval and Management

§        Import/export of standard image file formats and many commercial scanner formats.

§        Conversion to/from over 30 standard image formats, including the DICOM standard.

§        Template for specification of image information for unknown formats.

§        Automated construction of volume image files from groups of individual image files.

§        High fidelity, rapid image compression/decompression using wavelets.

§        Access to tape devices for I/O of image data in many formats.

§        Graphical file manager with iconic representation of images and other file types.

§        Direct drag and drop to/from the Analyze file manager and other Analyze programs.

o       Image Data Loading and Storing

§        Support for native image file formats without need for conversion.

§        Volume image resizing based on automated isotropic sampling (noncubic resizing).

§        Interactive subregioning, flipping, and padding of volume image.

§        Data type conversion with intensity windowing or thresholding.

§        Direct output to any supported file format.

o       2-D Image Generation and Display

§        Interactive reformatting and display of multiplanar images.

§        Interactive intensity windowing.

§        Interactive dissection and intersection through 3-D volumes.

§        Interactive oblique images through 3-D volumes.

§        Image volume reformatting along any arbitrary oblique axis.

§        Interactive generation of "curved" images and radial images.

§        Cine movie displays with multiple panels, variable size, and speed control.

o       3-D Image Generation and Display

§        Fully interactive volume rendering of 3-D images.

§        Both transmission and reflection raycasting models.

§        Depth, gradient, composited and phong shaded surfaces.

§        Voxel and object compositing with transparency.

§        Divergent perspective ray casting/rendering.

§        Interactive colorizing and voxel texture mapping.

§        Interactive, graphical control of all divergent viewing specifications.

§        Control of multiple viewing positions (cameras).

§        Sequence generation between camera positions for cine fly-throughs (e.g., virtual endoscopy).

§        Variable illumination and angle-of-view.

§        Variable render masks and dynamic preview modes.

§        Radial cylindrical and stereo-pair rendering.

§        Maximum intensity, integrated and surface projections.

§        Numerical projection rendering.

§        Multiplanar dissection and subregioning.

§        Interactive orthogonal and oblique sectioning.

§        Manual editing and automatic definition of objects.

§        Rendering of combined or individual segmented objects.

§        Interactive rendered object manipulation.

§        Mirror image rendering for independent objects.

§        Linear and curvilinear surface measurements.

§        Direct surface area and volumetric measurements.

§        Powerful, flexible movie generator with control of frame-to-frame updates of volume rendering parameters (e.g., rotations, dissections, dissolutions, etc.).

o       3-D Model Generation and Display

§        Automatic extraction of contours from isosurfaces or objects.

§        Output to common contour file formats (IGES, SLC, ASCII list).

§        Surface extraction from voxel-based structures using advanced algorithms:

§        Deformable model with adaptive surface fitting for surface extraction.

§        Marching cubes surface extraction.

§        Based on user-specification of a given number of desired polygons (polygonal budget)

§        Output to common surface file formats (IGES, DXF, OBJ, IV, STL, VRIO, VRML, POLY, PATRAN).

§        Model viewer for viewing multiple extracted surfaces (wireframe and shaded).

o       Image Processing

§        Image Calculator - metaphor of hand-held calculator for powerful algebraic and boolean operations on images.

§        Formula design and execution for customized 2-D and 3-D image processing.

§        Image algebra for combining images from formulas.

§        Mathematical, logical, and transcendental operations.

§        3-D matrix operations and geometric transformations.

§        Linear and adaptive histogram operations.

§        Spatial and frequency domain image processing.

§        User-defined convolution kernels.

§        Inhomogeneity correction based on statistical means filtering.

§        Interactive, graphic-based design of custom filters.

§        2-D and 3-D FFT and deconvolution routines.

§        Image transformation and compression using wavelets.

o       Image Segmentation

§        Interactive manual object segmentation.

§        2-D and 3-D region growing for object segmentation.

§        2-D and 3-D math morphology for object segmentation.

§        Automatic edge contour extraction.

§        Automated segmentation based on 3-D morphological processing.

§        User definition of bounded region on selected image(s) within volume to condition segmentation.

§        Output of binary or masked grayscale segmented volume to other Analyze programs.
 

o       Image Registration and Fusion

§        Fusion (registration and integration) of multimodal images.

§        Intra- and inter-modality registration.

§        Registration using advanced normalized mutual information maximization.

§        Permits registration without need for prior segmentation.

§        Registration using surface matching of common surfaces.

§        Efficient section-to-section registration for 3-D volumes of serial images.

§        Interactive plotting and measurement of line and trace profiles.

§        Interactive definition of multiple regions of interest.

§        Selection and automatic sampling of regions of interest.

§        Measurement of dimensions and densities.

§        Measurement of regional shape and texture.

§        ASCII data file format for exporting to standard analysis programs.

§        Analysis of tree structures (lengths, branching angles, cross-sectional areas).

§        Surface area and volume measurement by stereology.

o       Ancillary Functionality

§        Interactive screen editor with text, labels and graphics.

§        Hardcopy printing of text and images, including full color postscript.

§        Extensive interactive color definition and manipulation.

o       Documentation

§        On-line, context sensitive help documentation and tutorials.

§        Documentation in HTML format, use with web browsers.

o       File Formats

§        Analyze-Specific File Formats: AnalyzeAVW, AnalyzeAVW Volume Files, Analyze Image (7.5), Analyze Object Maps, Analyze (7.5) Screen Files.

§        Standard Radiological File Formats: DICOM, ACR-NEMA, PAPYRUS, INTERFILE.

§        Vendor-Specific Radiological File Formats: GE Advantage, GE Signa MRI, GE 9800 CT, GE Advance PET, GE Starcam, Siemens CT, Siemens MAGVIS, Siemens/CTI PET, IMATRON (EBCT), SMIS.

§        Common Raster File Formats: BMP, GIF, TIFF, PBM, PGM, PPM, PNG, TARGA, PIC, SGI rgb, Sun Rasterfiles, XBM, XWD, PostScript.

§        Common Movie File Formats: QUICKTIME, YUV.

§        Output surface file formats: Alias, IGES, SLC, ASII list, DXF, OBJ, IV, STL, VRIO, VRML, POLY, SSD, POGO, PATRAN, Inventor, Autocad.                  

5.   Web Resources