Journal Articles

  • Active learning boosts performance in STEM courses [Psychological and Cognitive Sciences]
    [Jun 2014]

    To test the hypothesis that lecturing maximizes learning and course performance, we metaanalyzed 225 studies that reported data on examination scores or failure rates when comparing student performance in undergraduate science, technology, engineering, and mathematics (STEM) courses under traditional lecturing versus active learning. The effect sizes indicate that on average,...
    Categories: Journal Articles
  • Explaining Asian Americans' academic advantage [Social Sciences]
    [Jun 2014]

    The superior academic achievement of Asian Americans is a well-documented phenomenon that lacks a widely accepted explanation. Asian Americans’ advantage in this respect has been attributed to three groups of factors: (i) socio-demographic characteristics, (ii) cognitive ability, and (iii) academic effort as measured by characteristics such as attentiveness and work...
    Categories: Journal Articles
  • In This Issue [This Week in PNAS]
    [Jun 2014]

    Active learning and STEM education A graduating class. Image courtesy of iStockphoto/janniswerner. The push to produce STEM teachers and graduates as a means of improving innovative capacity in the United States has raised the question of what constitutes effective STEM education. To investigate the success of different teaching methods, Scott...
    Categories: Journal Articles
  • Profile of Bruce Levin [Profiles]
    [Jun 2014]

    For population biologist Bruce Levin, opening the incubator to see how yesterday’s experiment worked is his ideal way to start the day. That anticipation has kept the Emory University professor of biology excited about his research on the population and evolutionary biology of bacteria for more than 40 years, and...
    Categories: Journal Articles
  • Large-scale comparison of STEM teaching methods [Psychological and Cognitive Sciences]
    [Jun 2014]

    The quality of science, technology, engineering, and mathematics (STEM) education in the United States has long been an area of national concern, but that concern has not resulted in improvement. Recently, there has been a growing sense that an opportunity for progress at the higher education level lies in the...
    Categories: Journal Articles
  • Asian Americans' academic advantage [Social Sciences]
    [Jun 2014]

    Scholars have long debated the reasons underlying Asian Americans’ exceptional educational outcomes. Psychologists emphasize individual cognitive ability and the effects of stereotypes on performance (1). Culturalists point to values, beliefs, norms, and behavioral patterns unique and intrinsic to ethnicity (2). Structuralists focus on socioeconomic status within and beyond the family,...
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  • Protein splicing hangs from the branch [Biochemistry]
    [Jun 2014]

    Inteins perform a macromolecular vanishing act that continues to impress as its secrets are revealed. Dispersed through all domains of life, these autocatalytic domains exit the folds of ostensibly unrelated proteins soon after translation. Inteins bust at the seams, severing peptide bonds that immediately precede and follow their sequence. Critically,...
    Categories: Journal Articles
  • Embryonic origin of subplate diversity [Neuroscience]
    [Jun 2014]

    An Extracortical Source of Subplate Neurons The proper wiring of neuronal circuits during development is a prerequisite for normal brain function. Moreover, complex brain function is possible in part because of the extraordinary diversity in neuronal cell types that provides the substrate for networks required for a variety of computational...
    Categories: Journal Articles
  • Catching up to human vision [Neuroscience]
    [Jun 2014]

    In the course of our daily lives, we rely on our ability to quickly recognize visual objects despite variations in the viewing angle or lighting conditions (1). Most of the time, this process occurs so naturally that it is easy to underestimate the computational challenge it poses. In fact, as...
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  • Mechanically tunable block polymers from sugar [Applied Biological Sciences]
    [Jun 2014]

    Development of sustainable and biodegradable materials is essential for future growth of the chemical industry. For a renewable product to be commercially competitive, it must be economically viable on an industrial scale and possess properties akin or superior to existing petroleum-derived analogs. Few biobased polymers have met this formidable challenge....
    Categories: Journal Articles
  • Boundary singularities in soap-film motion [Applied Mathematics]
    [Jun 2014]

    Recent work has shown that a Möbius strip soap film rendered unstable by deforming its frame changes topology to that of a disk through a “neck-pinching” boundary singularity. This behavior is unlike that of the catenoid, which transitions to two disks through a bulk singularity. It is not yet understood...
    Categories: Journal Articles
  • Navigability of interconnected networks [Applied Physical Sciences]
    [Jun 2014]

    Assessing the navigability of interconnected networks (transporting information, people, or goods) under eventual random failures is of utmost importance to design and protect critical infrastructures. Random walks are a good proxy to determine this navigability, specifically the coverage time of random walks, which is a measure of the dynamical functionality...
    Categories: Journal Articles
  • Nonequilibrium dynamics during viral DNA packaging [Biophysics and Computational Biology]
    [Jun 2014]

    Many viruses use molecular motors that generate large forces to package DNA to near-crystalline densities inside preformed viral proheads. Besides being a key step in viral assembly, this process is of interest as a model for understanding the physics of charged polymers under tight 3D confinement. A large number of...
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  • Terephthalic acid via Diels-Alder reactions [Chemistry]
    [Jun 2014]

    Terephthalic acid (PTA), a monomer in the synthesis of polyethylene terephthalate (PET), is obtained by the oxidation of petroleum-derived p-xylene. There is significant interest in the synthesis of renewable, biomass-derived PTA. Here, routes to PTA starting from oxidized products of 5-hydroxymethylfurfural (HMF) that can be produced from biomass are reported....
    Categories: Journal Articles
  • Asymmetric synthesis of remotely chiral 1-alkanols [Chemistry]
    [Jun 2014]

    Despite recent advances of asymmetric synthesis, the preparation of enantiomerically pure (≥99% ee) compounds remains a challenge in modern organic chemistry. We report here a strategy for a highly enantioselective (≥99% ee) and catalytic synthesis of various γ- and more-remotely chiral alcohols from terminal alkenes via Zr-catalyzed asymmetric carboalumination of...
    Categories: Journal Articles
  • Solid-state structures of peapod bearings [Chemistry]
    [Jun 2014]

    A supramolecular combination of carbon nanotube and fullerene, so-called a peapod, has attracted much interest, not solely because of its physical properties but also for its unique assembled structures of carbonaceous entities. However, the detailed structural information available was not sufficient for in-depth understanding of its structural chemistry or for...
    Categories: Journal Articles
  • Optimizing antibiotic treatment protocols [Population Biology]
    [Jun 2014]

    The successful treatment of bacterial infections is the product of a collaboration between antibiotics and the host’s immune defenses. Nevertheless, in the design of antibiotic treatment regimens, few studies have explored the combined action of antibiotics and the immune response to clearing infections. Here, we use mathematical models to examine...
    Categories: Journal Articles
  • Spraying to see cancer cells [Inner Workings]
    [Jun 2014]

    In a Stanford University operating room, surgeons peer into the abdomen of a patient, scalpels delicately dancing under the bright lights. They’re removing a gastric tumor, hoping they can cut away every cancerous cell. Just outside the operating room, an unlikely group waits to lend a hand: they’re not medical...
    Categories: Journal Articles
  • Cover 2 - Editorial Board
    [Jun 2014]

    Publication date: June 2014
    Source:Journal of Structural Biology, Volume 186, Issue 3









    Categories: Journal Articles
  • Table of Contents / barcode
    [Jun 2014]

    Publication date: June 2014
    Source:Journal of Structural Biology, Volume 186, Issue 3









    Categories: Journal Articles
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